SMILEs
STRUCTURAL MOLECULAR IMAGING LIGHT ENHANCED SPECTROSCOPIES

Investigation and comparison of amino acid, nucleic acids and basic proteins using Raman, SERS and Chiral Raman spectroscopy

Raman, SERS and Chiral Raman spectroscopy​ for Biomaterials​

Details

SERS substrates were fabricated by means of nanoimprinter and electroplating technique to obtain a matrix of gold nanograins. Various biomolecules (amino acids, nucleic acids and proteins) were deposited over Au-based surface enhanced Raman spectroscopy (SERS) substrate and over CaF2 substrate for reference Raman and Chiral Raman measurements. A database was created comparing Raman, SERS and Chiral Raman findings. The band assignment of all the peaks was discussed in detail.