SMILEs
STRUCTURAL MOLECULAR IMAGING LIGHT ENHANCED SPECTROSCOPIES

People

Gobind Das, PhD

Research Scientists

Introduction

Gobind Das pursued his Master of Sceince (Physics) and Master of Technology (Laser Science and Applications) from BHU, Varanasi, India (1997-1999) and DAVV, Indore, India (1999-2001), respectively. Later on, he joined Università degli studi di Trento, Trento for his Ph. D. (Physics). In year Dec. 2004, he defended his Ph.D. thesis entitled "Study of micro-structure and optical properties of silicon oxide-based materials by vibrational spectroscopy methods", supervisor: Prof. Gino Mariotto.

He had wide experience at Universities as a post-doc and in spin-off company, Catanzaro. He carried out his post-doc tenure at Faculty of engineering, University of Trento, Trento and at Faculty of medicine, University of Magna Graecia “Catanzaro”, Catanzaro.  Later on, he joined Istituto Italiano di Tecnologia, Genoa as a Team Leader before joining KAUST, Saudi Arabia as a research scientist. He is having various publications in reputed journals, having h factor of 23 and i10 of 46.

Research Interests

TERS over SERS substrate

Tip enhanced Raman scattering (TERS) is a near field technique. It allows the lateral resolution much below of diffraction limit (below 10 nm). TERS technique indeed deliver the spatial resolution of atomic force microscope with the chemical information of Raman spectroscopy. To enrich the information with better sensitivity, gold/silver based surface enhanced Raman scattering substrate will be employed.  In this regards, Graphene coated Au surface will be used. Furthermore, the tip will be electrochemically etched to have supersharp nosal AFM tip. Different biomaterials such as fibril proteins, lipid bilayers, double stranded DNA, etc. will be investigated.

Vibrational Optical Activity

Vibrational optical activity or Raman optical activity (ROA) is a new technique that relies on the difference in the intensity of Raman scattering from right and left circularly polarized light due to molecular Chirality. The technique provides not only the chemical figure-print of the molecule under investigation but also provide its orientation. The technique will be used for the protein samples to investigate the secondary/tertiary structure by varying the external conditions such as buffer pH, temperature etc.. In addition, most of the proteins are not yet analysed due to the fact of high fluorescence background and low ROA signal, a further effort will be made to make it possible incorporating it with plasmonics.

Selected Publications

M. Chirumamilla, A. Toma, A. Gopalakrishnan, G. Das, R. Proietti Zaccaria, and E. Di Fabrizio, 3D-nanostar Dimers with Sub-10 nm Gap for Single Molecule Surface Enhanced Raman Scattering, Advanced Materials, 26 (2014) 2353-2358.

G. Das, M. Chirumamilla, A. Toma, A. Gopalkrishana, R. Proietti Zaccaria, A. Alabastri, M. Leoncini and E. Di Fabrizio, Nanocuboid Plasmonic Structure: periodic SERS arrays for biosensor applications, Scientific Report, 3 (2013) 1792(1-6).

G. Das, N. Patra, A. Gopalakrishana, Remo Poietti Zaccaria, Andrea Toma, Sanjay Thorat, Enzo Di Fabrizio, Alberto Diaspro, and Marco Salerno, Fabrication of ordered and reproducible large-area nanostructures for SERS biosensor application, Analyst, 137 (2012) 1785-1792.

F. De Angelis, G. Das, P. Candeloro, M. Patrini, M. Galli, A. Bek, I. Maksymov, C. Liberale, L. C. Andreani, and E. Di Fabrizio, Nanoscale chemical mapping using three-dimesional adiabatic compression of surface plasmon polaritons, Nature Nanotechnology, 5 (2010) 67-72.

G. Das, F. Mecarini, F. Gentile, F. De Angelis, M. Kumar HG, P. Candeloro, C. Liberale, G. Cuda and E. Di Fabrizio, Nano-patterned SERS substrate: application for protein analysis vs. temperature, Biosensors and Bioelectronics, 24, (2009) 1693-1699.

Education

​Ph. D. (Physics) in 2004 from University of Trento, Italy

M. Tech. (Laser Science) in 2001 from D. A. V. V., Indore (M. P.), India

M. Sc. (Physics) in 1999 from B. H. U., Varanasi (U. P.), India